On October 10th at the Auditorium Colajanni of the University of Kore of Enna held the conference launch of the Interreg VA Italy – Malta cooperation project I Know – Interregional Key Networking for Open innovation empoWerment, with the aim of encouraging the creation of start-ups and the strengthening of SMEs competitive, with an Open Innovation approach, an opportunity to create development and business between the two islands. The event  was an opportunity to promote the acceleration seminars on Entrepreneurship, for students, researchers, entrepreneurs and experts.  At the end of the conference, a round table was held on the Open Innovation approach to promote the networking of experiences and professional skills, through best practices and success cases. Health and ICT entrepreneurs: Marco Pierotti – Cogentech, E. Spampinato – Consorzio Etna Hitech, and representatives of Sicilian Universities: R. Faraci, M. Limosani, S. Montresor participated.